Subcutaneous Tocilizumab May Be Less Effective than Intravenous Tocilizumab in the Treatment of Juvenile Idiopathic Arthritis-associated Uveitis.
نویسندگان
چکیده
Volume 44, no. 2 Uveitis associated − Tocilizumab in the Treatment of Juvenile Idiopathic Arthritis Subcutaneous Tocilizumab May Be Less Effective than Intravenous ESTEFANIA QUESADA-MASACHS and CONSUELO MODESTO CABALLERO http://www.jrheum.org/content/44/2/260 J Rheumatol 2017;44;260-261 http://www.jrheum.org/alerts 1. Sign up for TOCs and other alerts http://jrheum.com/faq 2. Information on Subscriptions http://jrheum.com/reprints_permissions 3. Information on permissions/orders of reprints
منابع مشابه
Managing juvenile idiopathic arthritis-associated uveitis.
Bilateral chronic anterior uveitis is an extra-articular feature of juvenile idiopathic arthritis. Although figures vary, uveitis occurs in approximately 11%-13% of patients with this disease and is most commonly associated with the female gender, oligoarthritis, and presence of antinuclear antibodies. The disease has an insidious onset and is often asymptomatic. Managing patients with juvenile...
متن کاملA phase II trial protocol of Tocilizumab in anti-TNF refractory patients with JIA-associated uveitis (the APTITUDE trial)
Background: Juvenile idiopathic arthritis (JIA) is the most common rheumatic disease in children. Children with JIA are at risk of intraocular inflammation (uveitis). In the initial stages of mild-moderate inflammation uveitis is asymptomatic. Most children with mild-moderate uveitis are managed on topical steroid drops with or without systemic methotrexate (MTX). When children with moderate-se...
متن کاملAcute anterior uveitis after discontinuation of tocilizumab in a patient with rheumatoid arthritis
BACKGROUND Tocilizumab is a humanized monoclonal anti-interleukin-6 (IL-6) receptor antibody and has been approved in Japan for the treatment of Castleman's disease, rheumatoid arthritis (RA), and systemic juvenile idiopathic arthritis. Conjunctivitis and dry eye are known ocular adverse effects, but uveitis has not been reported. CASE REPORT A 72-year-old woman had undergone bilateral catara...
متن کاملSystematic review on treatment of juvenile idiopathic arthritis – associated uveitis
Results Therapy of JIA-associated uveitis is guided by the severity of inflammation and complications. Topical corticosteroids are generally used as the initial treatment. Severe uveitis is commonly treated with immunosuppressive drugs. Methotrexate is presently the first-choice agent. If uveitis is not responding, another immunosuppressive agent or biological is applied. Currently, adalimumab ...
متن کاملTocilizumab (TCZ) may be an effective treatment for poly-juvenile idiopathic arthritis (pJIA) as for rheumatoid arthritis (RA)
Purpose TNF inhibitors are established treatment for poly-juvenile idiopathic arthritis (pJIA), but there are needs of alternative therapy for refractory patients. Tocilizumab (TCZ) has been widely used for rheumatoid arthritis (RA) in adults, and the effectiveness for systemic JIA has been well-documented. However, the experience on pJIA is limited. We compared the clinical courses of our pati...
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ورودعنوان ژورنال:
- The Journal of rheumatology
دوره 44 2 شماره
صفحات -
تاریخ انتشار 2017